Enantiomerically pure cyclohexanols and cyclohexane-1, 2-diol derivatives; chiral auxiliaries and substitutes for (–)-8-phenylmenthol. A facile enzymatic route

…, D Breitgoff, R Seemayer, MP Schneider

Index: Laumen, Kurt; Breitgoff, Detlef; Seemayer, Robert; Schneider, Manfred P. Journal of the Chemical Society, Chemical Communications, 1989 ,  # 3  p. 148 - 150

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Citation Number: 21

Abstract

A number of optically active cyclohexanol and cyclohexane-1, 2-diol derivatives, chiral auxiliaries and substitutes for (–)-and (+)-8-phenylmenthol, have been prepared by enzymatic hydrolysis of their racemic acetates and chloroacetates in the presence of highly selective ester hydrolase from Pseudomonas sp.(SAM–II).