Synlett

A Short and Efficient Synthesis of (-)-Diospongin A

C Bressy, F Allais, J Cossy

Index: Bressy, Cyril; Allais, Florent; Cossy, Janine Synlett, 2006 , # 20 p. 3455 - 3456

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Citation Number: 30

Abstract

1,7-Diarylheptanoids are present in a great variety of natural products which possess interesting biological properties. [1] For example, curcumin, a linear 1,7-diarylheptanoid, has antiproliferative activity against cancer cell lines and also inhibits nitric oxide formation. [2] The 1,7-diarylheptanoids A and B isolated from Ethlingera elatior were found to inhibit lipid peroxidation in a more potent manner than tocopherol [3] (Figure [1] ). Oreganin has been reported to have anti- ...