Tetrahedron letters

The isolation, structural determination, and total synthesis of terfestatin A, a novel auxin signaling inhibitor from Streptomyces sp.

A Yamazoe, K Hayashi, A Kuboki, S Ohira, H Nozaki

Index: Yamazoe, Atsushi; Hayashi, Ken-Ichiro; Kuboki, Atsuhito; Ohira, Susumu; Nozaki, Hiroshi Tetrahedron Letters, 2004 ,  vol. 45,  # 45  p. 8359 - 8362

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Citation Number: 17

Abstract

Indole 3-acetic acid, a plant hormone auxin, regulates every aspects of plant growth and development. In the screening for specific inhibitors on auxin signaling using the transgenic Arabidopsis plant harboring the auxin-responsive reporter gene, terfestain A was found to be a novel inhibitor of auxin signaling from the culture of Streptomyces sp. F40. The structure of terfestatin A was determined to be p-terphenyl β-glucoside on the basis of ...