The Journal of Organic Chemistry

Nucleic acid related compounds. 70. Synthesis of 2'(and 3')-deoxy-2'(and 3')-methyleneadenosines and bis (methylene) furan 4', 5'-didehydro-5'-deoxy-2'(and 3')- …

V Samano, MJ Robins

Index: Samano, Vicente; Robins, Morris J. Journal of Organic Chemistry, 1991 ,  vol. 56,  # 25  p. 7108 - 7113

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Citation Number: 23

Abstract

Tronchet and TroncheP prepared the first deoxymethylenenucleoside by condensation of a 3-methylene-cu-D-er~. ythro-pentofuranose derivative with 6-N-benzoyladenine chloromercury salt to give a mixture from which the@-anomer of 3 '-deoxy-3'- methyleneadenosine (7) was obtained. Ueda and co-workers have prepared 2 '-deoxy-2'- methyleneadenosinel'(1 1) and various alkyl-and alkylidenenucleoside derivatives. laJg ...