A nickel catalyst for the arylation and vinylation of lithium ester enolates

AA Millard, MW Rathke

Index: Millard,A.A.; Rathke,M.W. Journal of the American Chemical Society, 1977 , vol. 99, # 14 p. 4833 - 4835

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Citation Number: 97

Abstract

Sir. a-Aryl and a-vinyl carbonyl groupings are structural features of a large number of biologically important molecules. A method for the direct arylation or vinylation of enolate anions would greatly simplify the synthesis of such molecules. Progress to this goal has been reported by a number of workers,'with perhaps the most promising approach to date being the trapping of photogenerated aryl radicals with ketone enolates (the SRN~ ...