Nitric acid oxidation of d-mannose was carried out under an oxygen atmosphere using a computer controlled reactor. The process represents a catalytic oxidation of d-mannose with oxygen as the terminal oxidant. The crude oxidation product was esterified with methanolic HCl and the esterified product directly converted to crystalline N, N′-dimethyl-d- mannaramide with methylamine. Treatment of the diamide in aqueous sodium hydroxide ...
