Substituted amides and hydrazides of 1, 4-dicarboxylic acids. Part 8. Synthesis and hypoglycemic activity of substituted succinic acid amides and hydrazides

NV Kolotova, AV Dolzhenko, VO Koz'minykh…

Index: Kolotova; Dolzhenko; Koz'minykh; Kotegov; Godina Pharmaceutical Chemistry Journal, 1999 , vol. 33, # 12 p. 635 - 637

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Citation Number: 7

Abstract

The IH NMR spectra of the synthesized compounds were measured on the RYa-2310 (60MHz) and Varian VPX-300 (300 MHz) spectrometers using samples dissolved in DMSO- d6, with HMDS or TMS as the internal standard. The course of reactions was monitored and the purity of the reaction products was checked by TLC on Silufol UV-254 plates eluted in an ethyl acetate-hexane (5: 1) system and visualized by exposure to iodine vapors. The data ...