The Journal of Organic Chemistry

Metalation studies of trisubstituted oxazoles

BH Lipshutz, RW Hungate

Index: Lipshutz, Bruce H.; Hungate, Randall W. Journal of Organic Chemistry, 1981 , vol. 46, # 7 p. 1410 - 1413

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Citation Number: 43

Abstract

As a part of a program aimed at preparing new [mn]-heterocyclophanes containing an oxazole, imidazole, or isoxazole moiety in addition to a phenyl ring, we have initially chosen to examine the functionalization of trisubstituted oxazoles. These aromatic systems have found considerable utility as latent functional group equivalenta2 Furthermore, a number of interesting and biologically active natural products containing the oxazole nucleus, as ...