Chemosphere

Synthesis of polychlorinated biphenyls (PCBs) using the Suzuki-coupling

HJ Lehmler, LW Robertson

Index: Lehmler, Hans-Joachim; Robertson, Larry W Chemosphere, 2001 , vol. 45, # 2 p. 137 - 143

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Citation Number: 62

Abstract

An improved synthesis of polychlorinated biphenyls (PCBs) utilizing a palladium-catalyzed cross-coupling reaction (Suzuki-coupling) is described. The coupling of (chlorinated) aryl boronic acids 1–3 with bromochlorobenzenes 4 using the standard conditions of the Suzuki- coupling gave the desired PCB congeners 5–7 in good to excellent yields. The self-coupling product of the aryl boronic acids is the major impurity of this reaction. 3, 4, 5- ...