The Stereochemistry of Organometallic Compounds. LXI. The Preparation of Quinazolines and Quinazolinones Involving Rhodium-Catalyzed Hydroformylation of …

…, WR Jackson, QJ Mccubbin, AE Trnacek

Index: Campi, Eva M.; Jackson, W. Roy; McCubbin, Quentin J.; Trnacek, Andrew E. Australian Journal of Chemistry, 1994 , vol. 47, # 6 p. 1061 - 1070

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Abstract

Abstract Rhodium-catalysed reactions of ortho-alkenylaminobenzylamines or benzamides with H 2/CO give quinazolines and quinazolinones containing a fused alicyclic ring in excellent yields. Reactions of N-allyl derivatives give a single regioisomer. Reactions of but- 3-enyl analogues give readily separable mixtures of pyrrolo and pyrido derivatives. Their 3- methylbut-3-enyl analogues give the pyrido derivatives (12) and (13) in reactions which ...