The Journal of organic chemistry

Synthesis of fatty acids using organocopper (I) Ate complexes derived from Grignard reagents

D Bergbreiter, G Whitesides

Index: Bergbreiter,D.E.; Whitesides,G.M. Journal of Organic Chemistry, 1975 , vol. 40, p. 779 - 782

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Citation Number: 45

Abstract

Results Both primary and secondary Grignard reagents react with methyIcopper (1) and form copper (1) ate complexes that selectively transfer the alkyl group originally bonded to magnesium in high yield in alkylation reactions. By using the readily available methyl or ethyl ll-iodoundecanoate in this reaction, it is possible to synthesize a variety of fatty acids. A typical procedure-that for ethyl 21-do-