An improved procedure for the iodination of phenols using sodium iodide and tert-butyl hypochlorite

T Kometani, DS Watt, T Ji, T Fitz

Index: Kometani, Tadashi; Watt, David S.; Ji, Tae; Fitz, Tony Journal of Organic Chemistry, 1985 , vol. 50, # 25 p. 5384 - 5387

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Citation Number: 46

Abstract

Yield determined by conversion to Nn-butylamine derivative. Ji, TH; Ji, I. Anal. Chem. 1982, 121, 286. Balance of the product mixture in these cases was unreacted starting material. Conditions: A, 1.2 equiv NaI, 1.2 equiv chloramine T; B, 2.2 equiv NaI, 2.2 equiv chloramine T; C, 1.1 equiv NaI, 1.1 equiv t-BuOC1; D, 2.2 equiv NaI, 2.2 equiv t-BuOC1; E, 3.3 equiv NaI, 3.3 equiv t-BuOC1. hypochlorite or chloramine T were equally unrewarding. Although the ...