Organic & biomolecular chemistry

Highly efficient synthesis of 2, 5-disubstituted pyrazines from (Z)-β-haloenol acetates

Z Chen, D Ye, G Xu, M Ye, L Liu

Index: Chen, Zhengwang; Ye, Dongnai; Xu, Guohai; Ye, Min; Liu, Liangxian Organic and Biomolecular Chemistry, 2013 , vol. 11, # 39 p. 6699 - 6702

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Citation Number: 3

Abstract

A highly efficient synthesis of a wide range of 2, 5-disubstituted pyrazines from (Z)-β- haloenol acetates is described. The reactions are conducted under convenient conditions and provide products with excellent regioselectivity in moderate to excellent yields with a broad substrate scope, including a variety of aromatic and aliphatic haloenol acetates.

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