Abstract The interaction of sulfonamides with 4, 5-dihydroxyimidazolidin-2-ones was studied for the first time. The earlier unknown 4, 4′-sulfonyldiiminobis (1, 3-dialkylimidazolidin-2- ones) and 4 (5)-aryl (alkyl)-sulfonyliminoimidazolidin-2-ones were synthesized. A probable pathway of the reaction was proposed. 1, 3-Diethyl-4, 5-dihydroxyimidazolidin-2-one was isolated and described.