Synthesis, characterization, and antimicrobial screening of some Mannich base sydnone derivatives

PP Savaliya, VK Akbari, JA Modi, KC Patel

Index: Savaliya, Piyush P.; Akbari, Vikunjana K.; Modi, Jigisha A.; Patel, Keshav C. Medicinal Chemistry Research, 2013 , vol. 22, # 12 p. 5789 - 5797

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Citation Number: 4

Abstract

Abstract The title compounds (5a–j),(6a–j), and (7a–j) were prepared via a four-step procedure using starting material 4-methoxyaniline (1). The structure of all synthesized compounds was confirmed by FT-IR, 1 H NMR, 13 C NMR, and CHN analysis. The synthesized compounds were tested for their antibacterial and antifungal activity (MIC) in vitro against organisms viz. B. subtilis, S. aureus, E. coli, P. aeruginosa, and C. albicans ...