Ring-closing metathesis (RCM)[ 6 ] has become one of the most efficient ways to assemble macrocycles.[ 7 ] Several macromolecules are known to play an important role in bioorganic and medicinal chemistry, they possess unique chemical properties and play a pivotal role in host–guest[ 8 ] and supramolecular chemistry.[ 9 ] Synthesis of cyclophane derivatives is a challenging task because of the entropy factors and ring strain involved with these systems. These ...
