... Volume: Page: ... Method D: Et 3 N (0.40 mmol) added to a solution of the nucleophile (0.20 mmol) and 4 (0.40 mmol) in THF (1.0 mL); mixture stirred at 65 °C for 18 h. ... Solvent ratios for chromatography and R f values are reported as v/v ratios. ...