Synthesis

Tin (II) compounds as catalysts for the Kabachnik-Fields reaction under solvent-free conditions: Facile synthesis of α-aminophosphonates

R Gallardo-Macias, K Nakayama

Index: Gallardo-Macias, Ricardo; Nakayama, Kensaku Synthesis, 2010 , # 1 p. 57 - 62

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Citation Number: 27

Abstract

Abstract In the presence of a catalytic amount of tin (II) salts, the three-component Kabachnik- Fields reaction involving aldehydes, amines, and diethyl phosphite proceeded smoothly to afford the corresponding α-aminophosphonates in good to high yields. These reactions were carried out under solvent-free conditions.