Helvetica chimica acta

Permanganate oxidation of quinoxaline and its derivatives

CA Obafemi, W Pfleiderer

Index: Obafemi, Craig A.; Pfleiderer, Wolfgang Helvetica Chimica Acta, 1994 , vol. 77, # 6 p. 1549 - 1556

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Citation Number: 35

Abstract

Abstract The oxidation reactions of a series of quinoxaline derivatives, using KMnO 4 in the presence or absence of NaOH, are described. Neutral oxidation of 2-chloro-and 2, 3- dichloroquinoxalines 2–4 afforded the corresponding chloro-and dichloropyrazinedicarboxylic acids 13 and 14 in good yield. On the other hand, oxidation of quinoxalin-2 (1H)-one and 1, 4-dihydroquinoxaline-2, 3-dione derivatives in alkaline ...