N-(1, 2-Diphenylethyl) piperazines: A new class of dual serotonin/noradrenaline reuptake inhibitor

…, PV Fish, A Stobie, F Wakenhut, GA Whitlock

Index: Jonathan Fray; Bish, Gerwyn; Brown, Alan D.; Fish, Paul V.; Stobie, Alan; Wakenhut, Florian; Whitlock, Gavin A. Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 16 p. 4345 - 4348

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Citation Number: 24

Abstract

Download PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... The synthesis and structure–activity relationships of a novel series of piperazine derivatives as dual inhibitors of serotonin and noradrenaline reuptake is described. Two compounds possessed comparable in vitro profiles to the dual reuptake inhibitor duloxetine. ... The synthesis and structure– ...