Results Synthesis. The synthesis of 3-ethoxy-3-methylpent-4-en-2-one (6a) was accomplished using three different synthetic schemes, the most efficacious of which is summarized in eq 1. The dithiane 9 was available from an intermediate step in the synthesis of Z7J2J3 Addition of sodium hydride to a solution of the dithioketal9 and ethyl iodide in dry dimethylformamide at 0" C gave 92% of the ether 10. Mercuric chloride cleavageI2 of the ...
