e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Experimental and theoretical investigations of ring-expansion in 1-methylcyclopropylcarbene
…, JR Snoonian, HM Sulzbach, CM Hadad
Index: Thamattoor, Dasan M.; Snoonian, John R.; Sulzbach, Horst M.; Hadad, Christopher M. Journal of Organic Chemistry, 1999 , vol. 64, # 16 p. 5886 - 5895
1-Methylcyclopropylcarbene, generated by photolysis of two isomeric hydrocarbon precursors, undergoes ring-expansion readily to give 1-methylcyclobutene. Experimentally, intramolecular carbon-hydrogen insertions are not observed. Trapping studies with TME demonstrates the formation of the expected cyclopropane adduct, and via a double- reciprocal analysis, the lifetime of 1-methylcyclopropylcarbene was determined to be 12 ...