R e conclude that the interaction of amines with photoexcited chlorophenothiazines 1 and 5 contributes to their photoreactivity. However, even in the absence of the side chain, 5 is still decomposed rather efficiently (4= 0.2). This makes it relatively unlikely that a photostable drug of the chlorpromazine family can be synthesized merely by altering the constitution of the side chain of the drug. On photochemical grounds. substitution of the chlorine atom ...
