Pesticide science

Effects of anti??ecdysteroid azole analogues of metyrapone on the larval development of the fleshfly, Neobellieria bullata

I Bélai, B Darvas, K Bauer, MH El??Din

Index: Belai, Ivan; Darvas, Bela; Bauer, Krisztina; Tag El-Din, Mahmoud H. Pesticide Science, 1995 , vol. 44, # 3 p. 225 - 232

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Citation Number: 17

Abstract

Abstract Based on our previous finding that PIM (phenyl-imidazolyl-metyra-pon; 2-(1- imidazolyl)-2-methyl-1-phenylpropan-1-one, 1) is a strong inhibitor of ecdysone 20- monooxygenase (IC 50= 7.89× 10− 7 M) from the fleshfly, Neobellieria bullata (Parker) and has also a good toxic action in vivo against this insect, 17 imidazole and 1, 2, 4-triazole analogues of metyrapone were synthesized and evaluated for their action against N. ...