Novel syntheses of symmetrical 2, 5-diaryl-1, 3, 4-oxadiazoles and 1, 4-phenylenebis-1, 3, 4-oxadiazoles

LI Belen'Kii, SI Luiksaar, IS Poddubnyi…

Index: Belen'kii; Luiksaar; Poddubnyi; Krayushkin Russian Chemical Bulletin, 1998 , vol. 47, # 11 p. 2238 - 2245

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Citation Number: 13

Abstract

Abstract The reactions of trichloromethylarenes with excess hydrazine hydrate in ethanol gives symmetrical 2, 5-diaryl-1, 3, 4-oxadiazoles in 68–96% yields. The reaction of 1, 4-bis (trichloromethyl) benzene with acylhydrazines in an ethanol-pyridine mixture gives the corresponding substituted or unsubstituted 1, 4-phenylenebis-1, 3, 4-oxadiazoles in 35– 51% yields. The mass spectra of 2, 5-diaryl-1, 3, 4-oxadiazoles and 1, 4-phenylenebis-1, 3 ...