Synthesis of 6-and 8-Phenyl-substituted Flavonoids

H Matsumura, T Tsuchiya, T Takeda…

Index: Matsumura; Tsuchiya; Takeda; Imafuku Bulletin of the Chemical Society of Japan, 1983 , vol. 56, # 7 p. 2037 - 2043

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Citation Number: 12

Abstract

3-Acetylbiphenyl-4-ol and-2-ol were condensed with substituted benzaldehydes to give respectively 5′-and 3′-phenyl-substituted chalcones (1a–k), which were cyclized to afford 6-and 8-phenylflavanones. The chalcones (1a–k) also gave the corresponding 6-and 8- phenylflavones via dibromides. The effects of the phenyl group on the spectral data are also discussed.