Cyclic amidines derived from benz [c, d] indole and 4, 5-dihydro-3H-1-benzazepine including some related compounds: Synthesis and pharmacological screening

M Protiva, Z Šedivý, J Holubek, E Svátek…

Index: Protiva; Sedivy; Holubek; et al. Collection of Czechoslovak Chemical Communications, 1985 , vol. 50, # 8 p. 1888 - 1898

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Abstract

Abstract Reactions of naphthostyril (I) with primary and secondary amines and titanium tetrachloride afforded cyclic amidines III-IX. Hydrogenation of I on Pd-C resulted in the 6, 7, 8, 8a-tetrahydro derivative X which gave by treatment with sodium amide and 3- ...