Tetrahedron letters

Alkylation of stabilized acetylides in DMSO. Preparation of α, β-acetylenic alcohols and acetals.

JM Chong, S Wong

Index: Chong, J. Michael; Wong, Susanna Tetrahedron Letters, 1986 , vol. 27, # 45 p. 5445 - 5448

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Citation Number: 18

Abstract

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Alkylation of stabilized acetylides in DMSO. Preparation of α,β-acetylenic alcohols and acetals. ... Stabilized terminal acetylenes 1 [eg R=CH 2 OTHP, Ph, CH(OEt) 2 ] may be converted into lithioacetylides and readily alkylated with 1° alkyl halides in DMSO to afford ...