Although thiamorpholine is structurally uncomplicated, only two methods for its synthesis have been described1s2 and only three references to its preparation were found in the literature. l-3 These procedures require as starting materials either 2-aminoethyl mercaptan or bis-(2-chloroethyl) sulfide, neither of which is conveniently handled, and the one reported yield is 3070.3 We have prepared thiamorpholine in about 70y0 yield by the reduction of 3 ...
