e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Tetrahedron letters
A highly effective quenching method of 1, 3-dipolar cycloadditions of nitrile oxides or nitrile oxide/Lewis acid complexes by use of 2-propenyloxymagnesium bromide
Abstract 2-Propenyloxymagnesium bromide, readily prepared by treating 2-propen-l-ol with EtMgBr, is a highly effective quencher of nitrile oxide cycloadditions since this alkoxide is much more reactive to nitrile oxides than any other ever known dipolarophiles of the electron- deficient, electron-rich, and strained types, including 3-buten-2-one, ethyl vinyl ether, and norbornene, respectively. This quencher is also effectively utilized to terminate the dipolar ...
