Tetrahedron Letters

Synthesis of cis, cis-diunsaturated α-meromycolic acid by a palladium-catalysed alkyl–alkyl Negishi reaction

G Berretta, GD Coxon

Index: Berretta, Giacomo; Coxon, Geoffrey D. Tetrahedron Letters, 2012 , vol. 53, # 2 p. 214 - 216

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Citation Number: 5

Abstract

Palladium-catalysed cross-coupling reactions between organo-metallic reagents and organic electrophiles are important transformations in organic synthesis. 1 Nevertheless, despite the fact that the importance of cross-coupling reactions in the synthesis of heterocyclic compounds is indisputable, the applicability of these transformations in the synthesis of lipids has been limited. In particular, alkyl–alkyl cross-coupling reactions of unactivated alkyl halides ...