Journal of the Chemical Society, Perkin Transactions 2

5-(Diethoxyphosphorylmethyl)-5-methyl-4, 5-dihydro-3H-pyrrole N-oxide: synthesis and evaluation of spin trapping properties

FL Moigne

Index: Roubaud, Valerie; Mercier, Anne; Olive, Gilles; Le Moigne, Francois; Tordo, Paul Journal of the Chemical Society. Perkin Transactions 2, 1997 , # 9 p. 1827 - 1830

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Citation Number: 22

Abstract

A new spin trap, the 5-(diethoxyphosphorylmethyl)-5-methyl-4, 5-dihydro-3H-pyrrole N-oxide (3), is prepared through a four-step synthetic route. The in vitro spin trapping properties of 3 have been investigated and the hydroxyl and superoxide spin adducts characterised. The persistence of the superoxide spin adduct obtained with 3 is compared with those of the analogues obtained with DEPMPO [5-(diethoxyphosphoryl)-5-methyl-4, 5-dihydro-3H- ...