Steric effects in the dehydrohalogenation of 7??halo??bicyclo [3.2. 0] hept??2??en??6??ols

R Huston, M Rey, AS Dreiding

Index: Huston,R. et al. Bulletin des Societes Chimiques Belges, 1979 , vol. 88, p. 911 - 921

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Citation Number: 2

Abstract

Abstract Experiments are presented which show that base treatment of the 7-halobicyclo- [3.2. 0] hept-2-en-6-ols 1 to 4 produces ring contraction to the aldehydes 5 and 6, except in those cases of the isomer series 4 where the substituent on the endo-side of C (7) is larger than a chlorine atom, in which case endo-hydrogen migration occurs to give the ketones 7.