Abstract Substitution of the allylic moiety of azatrienes by functionalized alkyl groups permits high chemical yields and stereoselectivity during IMDA cyclization. Substituted hydroisoindoles, precursors for natural and pharmaceutical products were prepared with good yields and selectivity.
[Cancho, Yolanda; Martin, Joan M.; Martinez, Maria; Llebaria, Amadeu; Moreto, Josep M.; Delgado, Antonio Tetrahedron, 1998 , vol. 54, # 7 p. 1221 - 1232]