Heterocycles

Synthesis and reactions of 3-and 8-ethynyl-1-azaazulenes

H Fujii, N Abe, N Umeda, A Kakehi

Index: Fujii, Hiroyuki; Abe, Noritaka; Umeda, Noritaka; Kakehi, Akikazu Heterocycles, 2002 , vol. 58, p. 283 - 292

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Citation Number: 5

Abstract

Abstract—3-Iodo-l-azaazulenes were easily ethynylated by Sonogashira-Hagihara reaction to give 3-ethynyl-l-azaazulenes. Cyclization of 2-amino-3-ethynyl-1-azaazulene was achieved by heating in the presence of copper (II) acetate or copper (II) trifluoromethanesulfonate, and l, 9-diaza-l#-cyclopent [û] azulene derivatives were obtained. Reaction of 2-chloro-lazaazulene with lithium phenylacetylide gave 3-chloro-l-(2-chloro-l- ...