A series of halophenols was prepared by the reaction of bis (hydroxyphenyl) methanes with effective halogenating agents such as bromine and sulfuryl chloride. One of these compounds, a biologically active halophenol—2, 2′, 3, 3′-tetrabromo-4, 4′, 5, 5′- tetrahydroxydiphenylmethane (1)—frequently isolated from red algae, was synthesized for the first time. Other halophenols included several novel compounds, together with known ...