Synthesis and biological properties of some heterocyclic derivatives of guanidine

…, VF Vasil'eva, IY Korsakova, VA Galitsina…

Index: Shvedov, V. I.; Vasil'eva, V. F.; Korsakova, I. Ya.; Galitsina, V. A.; Medvedev, B. A.; et al. Pharmaceutical Chemistry Journal, 1980 , vol. 14, # 8 p. 532 - 538 Khimiko-Farmatsevticheskii Zhurnal, 1980 , vol. 14, # 8 p. 38 - 43

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Abstract

Continuing our work on the synthesis and investigation of the biological properties of guanidine derivatives of quinoline and tetrahydroquinoline [i], we have synthesized lguanidinomethyl tetrahydroquinoline (I), 6-guanidinomethyltetrahydrocarbazole (II), and 2- guanidinoquinazoline (III), and studied their properties. Compound I was prepared from 4- phenyl-l, 2, 3, 4-tetrahydroquinoline (IV), which in turn was obtained by the reduction of ...