The Journal of organic chemistry

Palladium (0)-catalyzed Suzuki-Miyaura cross-coupling reactions of potassium aryl-and heteroaryltrifluoroborates with alkenyl bromides

GA Molander, T Fumagalli

Index: Molander, Gary A.; Fumagalli, Tiziano Journal of Organic Chemistry, 2006 , vol. 71, # 15 p. 5743 - 5747

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Citation Number: 57

Abstract

Efficient palladium (0)-catalyzed Suzuki-Miyaura cross-couplings are described. The reactions involving potassium aryl-and heteroaryltrifluoroborates with alkenyl bromides can generally be carried out using≤ 2 mol% of palladium catalyst and 3 equiv of base in toluene/H2O. When stereodefined alkenyl bromides are employed, the resulting styrene derivatives are accessed stereospecifically. A variety of functional groups are tolerated in ...