A synthetic way for the construction of the tetracyclic 1, 2, 3, 4, 5, 6-hexabydro-1, 5- methanoazocino [4, 3-b] indo1e system I, having a methoxycarbonyl substituent at the C-6 position, is reported. The synthesis implies methoxycarbonylation of the Interannular methylene carbon of an appropriate 2-(4-pyridylmethyl) indole, followed by alkylation of the pyridine nitrogen, catalytic hydrogenation and, finally, oxidative cyclization of the resulting ...
