Characteristic ion clusters as determinants for the identification of pyrrolizidine alkaloid N??oxides in pyrrolizidine alkaloid–containing natural products using HPLC–MS …

J Ruan, N Li, Q Xia, PP Fu, S Peng…

Index: Ruan, Jianqing; Li, Na; Xia, Qingsu; Fu, Peter P.; Peng, Shuying; Ye, Yang; Lin, Ge Journal of Mass Spectrometry, 2012 , vol. 47, # 3 p. 331 - 337

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Citation Number: 18

Abstract

In the recent decades, the use of herbal products has been rapidly growing worldwide, which makes the safety assessment of these products more challenging than ever before.[1, 2] As a result, the safety of natural products has drawn global attention. Among the natural toxins, pyrrolizidine alkaloids (PAs) are probably one of the most significant groups. More than 660 PAs have been identified in more than 6000 plants distributed in many ...