Tetrahedron Letters

Synthesis of alkyloxy stilbenes by one-pot O-alkylation-Wittig and O-alkylation-Wittig–Heck reaction sequence

KN Patel, BV Kamath, AV Bedekar

Index: Patel, Krupa N.; Kamath, Bola V.; Bedekar, Ashutosh V. Tetrahedron Letters, 2013 , vol. 54, # 1 p. 80 - 84

Full Text: HTML

Citation Number: 7

Abstract

A new route for the synthesis of alkyloxy stilbenes from hydroxy benzaldehydes is developed by a combination of one-pot reactions. Tandem one-pot O-alkylation-Wittig and O- alkylation-Wittig–Heck reactions offer a simple access to conjugated alkyloxy stilbenes. A highly conjugated tetra (p-alkyloxystyryl) benzene was synthesized from 1, 2, 4, 5- tetrabromobenzene involving a series of one-pot operations following the O-alkylation- ...