Synthesis of spiro [isoquinoline-4, 4′-pyran]-3-imines

MO Platonov, EO Kostyrko, VR Kovtunenko

Index: Kisel'; Platonov; Kostyrko; Kovtunenko Chemistry of Heterocyclic Compounds, 2000 , vol. 36, # 8 p. 905 - 910

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Citation Number: 2

Abstract

Abstract A method has been developed for the synthesis of 4-[2-(bromomethyl) phenyl] tetrahydro-2H-4-pyrancarbonitrile and a study was carried out on the reaction of this compound with primary amines, which, depending on the conditions, leads to either 4-[2-(R-