e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Copper (I) complexes from 1-bromopropyn-3-ols, dimethylformamide and copper (I) cyanide and their conversion to hydroxyacetylenic nitriles and hexadiynediols
SR Landor, B Demetriou, R Grzeskowiak…
Index: Landor,S.R. et al. Journal of Organometallic Chemistry, 1975 , vol. 93, p. 129 - 137
Abstract Copper (I) complexes of approximate composition (CuCN) 4·(DMF) 2· RR′ C (OH) C CBr have been isolated from copper (I) cyanide and 1-bromopropyn-3-ols in dry dimethylformamide (DMF). Decomposition of thes complexes with aqueous DMF gives 4- hydroxybutynenitriles in about 60% yield. For preparative purposes it is not necessary to isolate the complex, similar yields being obtained in a one step process. Decomposition of ...