Canadian journal of chemistry

Metabolites of Lachnellula fuscosanguinea (Rehm). Part 1. The isolation, structure determination, and synthesis of lachnelluloic acid

WA Ayer, JDF Villar

Index: Ayer, William A.; Villar, J. Daniel Figueroa Canadian Journal of Chemistry, 1985 , vol. 63, p. 1161 - 1165

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Citation Number: 16

Abstract

The metabolites produced in liquid culture by the fungus Lachnellula fuscosanguinea (Rehm) Dennis have been examined and two antifungal agents, lachnelluloic acid and lachnellulone, have been isolated. The structure of lachnelluloic acid has been established as (-)-4-hydroxy-3-octanoyl-6-pentyl-5, 6-dihydro-2-pyrone (1) by chemical and spectroscopic methods. The total synthesis of racemic lachnelluloic acid, starting from 6, 8 ...