Reaction of 6-methyl-2-(2-oxo-2-phenyl-ethylidene)-2, 3-dihydropyrimidin-4 (1H)-one with hydrazine and hydroxylamine

AA Yavolovskii, LV Grishchuk, IM Rakipov…

Index: Yavolovskii; Grishchuk; Rakipov; Stepanov; Ivanov, Yu. E.; Kamalov Chemistry of Heterocyclic Compounds, 2013 , vol. 48, # 10 p. 1487 - 1491 Khim. Geterotsikl. Soedin., 2012 , vol. 48, # 10 p. 1598 - 1602,5

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Citation Number: 3

Abstract

The reaction of 6-methyl-2-(2-oxo-2-phenylethylidene)-2, 3-dihydropyrimidin-4 (1 H)-one and of its nitrosation product with hydroxylamine stops at the stage of forming the corresponding oximes. The reaction of 6-methyl-2-(2-oxo-2-phenylethylidene)-2, 3- dihydropyrimidin-4 (1 H)-one with hydrazine yields a mixture of 3-amino-5-phenylpyrazole and 3-methyl-2-pyrazolin-5-one in 71 and 62% yields, respectively. The ketoxime is used ...