Potential antidiarrheal agents: 1-(11-Cyano-6, 11-dihydrodibenzo [b, e] thiepin-11-yl-alkyl)-and 1-(10-cyano-10, 11-dihydrodibenzo [b, f] thiepin-10-yl-alkyl)-4- …

K Šindelář, J Metyš, M Protiva

Index: Sindelar; Metys; Protiva Collection of Czechoslovak Chemical Communications, 1985 , vol. 50, # 5 p. 1089 - 1096

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Abstract

Abstract Substitution reactions of 11-(2-bromoethyl)-and 11-(3-bromopropyl)-6, 11- dihydrodibenzo [b, e] thiepin-11-carbonitrile and further of 10-(2-bromoethyl)-and 10-(3- bromopropyl)-10, 11-dihydrodibenzo [b, f] thiepin-10-carbonitrile with ethyl 4- phenylpiperidine-4-carboxylate, 4-phenylpiperidin-4-ol, 4-(2-tolyl) piperidin-4-ol, 4-(4- fluorophenyl) piperidin-4-ol, 4-(2-oxobenzimidazolin-1-yl)-piperidine and 1-phenyl-1, 3, 8- ...