Synthesis of the. beta.-adrenergic blocking agent timolol from optically active precursors

LM Weinstock, DM Mulvey, R Tull

Index: Journal of Organic Chemistry, , vol. 41, # 19 p. 3121 - 3124

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Citation Number: 68

Abstract

... The mixture was extracted twice with 35 ml of methylene chloride and the combined organic phases back-extracted twice with 50 ml of ... J. Med ... into s- triazolo[l,5-~]pyridines 4.9 Results In order to develop a reaction that could be extended to carbohydrate chemistry, we condense ...