The rates of reduction of a series of 1-(Z-benzyl) nicotinonitrile cations by a series of 1-(X- benzyl)-1, 4-dihydronicotinamides have been studied at 25° C in 20% CH3CN-80% H2O (pH 7.0 (5 m M phosphate), ionic strength 1.0 (KCl)). Spectral studies indicate the formation of 1, 4-dihydronicotinonitrile products, without the formation of the isomeric 1, 2-dihydro-or 1, 6-dihydro-nicotinamide intermediates. Second-order rate constants (k 2) for these ...
