Organic letters

Cobalt-Catalyzed Efficient Aziridination of Alkenes

GY Gao, JD Harden, XP Zhang

Index: Gao, Guang-Yao; Harden, Jeremiah D.; Zhang, X. Peter Organic Letters, 2005 , vol. 7, # 15 p. 3191 - 3193

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Citation Number: 94

Abstract

Cobalt porphyrins are capable of catalyzing the aziridination of alkenes with bromamine-T as the nitrene source. Among cobalt complexes of different porphyrins, Co (TDClPP) is an effective catalyst that can aziridinate a wide variety of alkenes. The catalytic system can operate at room temperature in a one-pot fashion with alkenes as limiting reagents, forming the desired N-sulfonylated aziridine derivatives in high to excellent yields with NaBr as the ...