. gamma.-Aminobutyric acid esters. 2. Synthesis, brain uptake, and pharmacological properties of lipid esters of. gamma.-aminobutyric acid

JN Jacob, VE Shashoua, A Campbell…

Index: Jacob; Shashoua; Campbell; Baldessarini Journal of Medicinal Chemistry, 1985 , vol. 28, # 1 p. 106 - 110

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Citation Number: 54

Abstract

Two lipid esters of U-'* C-labeled and unlabeled y-aminobutyric acid (GABA) were synthesized to test the possibility that natural lipid analogues, which resemble normal components of lipid bilayer membranes, can penetrate the blood-brain barrier and ...